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acute lymphoblastic leukemia cell line molt  (ATCC)


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    ATCC acute lymphoblastic leukemia cell line molt
    Acute Lymphoblastic Leukemia Cell Line Molt, supplied by ATCC, used in various techniques. Bioz Stars score: 98/100, based on 1906 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/acute+lymphoblastic+leukemia+cell+line+molt/MOLT-4/us12533357-150-60-69
    Average 98 stars, based on 1906 article reviews
    acute lymphoblastic leukemia cell line molt - by Bioz Stars, 2026-10
    98/100 stars

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    Control:

    Article Title: Treatment for acute myeloid leukemia or myelodysplastic syndrome
    Article Snippet: .. Vehicle control group Water (10 mL/kg) Positive control Group Vincristine diluted in PBS before dosing Route of administration PO (oral), daily for Compound (I), IP (intraperitoneal injection), weekly for vincristine Tumor cell type and line MOLT-4 acute lymphoblastic leukemia Number of cells and 1 × 107 cells in a volume of 0.1 ml volume injected Tumor Cell Culture: The human acute lymphoblastic leukemia cell line MOLT-4 was acquired from American Type Culture Collection (Manassas, VA, USA) and grown in RPMI medium containing 100 units/mL penicillin G sodium, 100 μg/mL streptomycin sulfate. ..

    Positive Control:

    Article Title: Treatment for acute myeloid leukemia or myelodysplastic syndrome
    Article Snippet: .. Vehicle control group Water (10 mL/kg) Positive control Group Vincristine diluted in PBS before dosing Route of administration PO (oral), daily for Compound (I), IP (intraperitoneal injection), weekly for vincristine Tumor cell type and line MOLT-4 acute lymphoblastic leukemia Number of cells and 1 × 107 cells in a volume of 0.1 ml volume injected Tumor Cell Culture: The human acute lymphoblastic leukemia cell line MOLT-4 was acquired from American Type Culture Collection (Manassas, VA, USA) and grown in RPMI medium containing 100 units/mL penicillin G sodium, 100 μg/mL streptomycin sulfate. ..

    Injection:

    Article Title: Treatment for acute myeloid leukemia or myelodysplastic syndrome
    Article Snippet: .. Vehicle control group Water (10 mL/kg) Positive control Group Vincristine diluted in PBS before dosing Route of administration PO (oral), daily for Compound (I), IP (intraperitoneal injection), weekly for vincristine Tumor cell type and line MOLT-4 acute lymphoblastic leukemia Number of cells and 1 × 107 cells in a volume of 0.1 ml volume injected Tumor Cell Culture: The human acute lymphoblastic leukemia cell line MOLT-4 was acquired from American Type Culture Collection (Manassas, VA, USA) and grown in RPMI medium containing 100 units/mL penicillin G sodium, 100 μg/mL streptomycin sulfate. ..

    Cell Culture:

    Article Title: Treatment for acute myeloid leukemia or myelodysplastic syndrome
    Article Snippet: .. Vehicle control group Water (10 mL/kg) Positive control Group Vincristine diluted in PBS before dosing Route of administration PO (oral), daily for Compound (I), IP (intraperitoneal injection), weekly for vincristine Tumor cell type and line MOLT-4 acute lymphoblastic leukemia Number of cells and 1 × 107 cells in a volume of 0.1 ml volume injected Tumor Cell Culture: The human acute lymphoblastic leukemia cell line MOLT-4 was acquired from American Type Culture Collection (Manassas, VA, USA) and grown in RPMI medium containing 100 units/mL penicillin G sodium, 100 μg/mL streptomycin sulfate. ..



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    Fig. 1. The cytotoxic effect of compound 11 against various cancer cell lines. Cell viability was measured in (A) acute leukemia cell lines: acute myeloid leukemia cells (MOLM-13 and MV4-11), acute promyelocytic leukemia cell (HL-60) and acute <t>lymphoblastic</t> leukemia cell (MOLT-4), and (B) solid tumor cell lines: ovarian (A2780), breast (MDA-MB-231), colorectal (HCT116) and pancreatic (AsPC-1) cancer cells. All cell lines were treated with compound 11 (at 0.3, 1, 3, 10 and 30 μM) for 72 h. The gray dotted line indicates 50% of cell viability. (C) The 50% inhibitory concentration (IC50) values are represented as the mean ± SD of three in dependent experiments.
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    Fig. 1. The cytotoxic effect of compound 11 against various cancer cell lines. Cell viability was measured in (A) acute leukemia cell lines: acute myeloid leukemia cells (MOLM-13 and MV4-11), acute promyelocytic leukemia cell (HL-60) and acute <t>lymphoblastic</t> leukemia cell (MOLT-4), and (B) solid tumor cell lines: ovarian (A2780), breast (MDA-MB-231), colorectal (HCT116) and pancreatic (AsPC-1) cancer cells. All cell lines were treated with compound 11 (at 0.3, 1, 3, 10 and 30 μM) for 72 h. The gray dotted line indicates 50% of cell viability. (C) The 50% inhibitory concentration (IC50) values are represented as the mean ± SD of three in dependent experiments.
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    Fig. 1. The cytotoxic effect of compound 11 against various cancer cell lines. Cell viability was measured in (A) acute leukemia cell lines: acute myeloid leukemia cells (MOLM-13 and MV4-11), acute promyelocytic leukemia cell (HL-60) and acute <t>lymphoblastic</t> leukemia cell (MOLT-4), and (B) solid tumor cell lines: ovarian (A2780), breast (MDA-MB-231), colorectal (HCT116) and pancreatic (AsPC-1) cancer cells. All cell lines were treated with compound 11 (at 0.3, 1, 3, 10 and 30 μM) for 72 h. The gray dotted line indicates 50% of cell viability. (C) The 50% inhibitory concentration (IC50) values are represented as the mean ± SD of three in dependent experiments.
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    Fig. 1. The cytotoxic effect of compound 11 against various cancer cell lines. Cell viability was measured in (A) acute leukemia cell lines: acute myeloid leukemia cells (MOLM-13 and MV4-11), acute promyelocytic leukemia cell (HL-60) and acute lymphoblastic leukemia cell (MOLT-4), and (B) solid tumor cell lines: ovarian (A2780), breast (MDA-MB-231), colorectal (HCT116) and pancreatic (AsPC-1) cancer cells. All cell lines were treated with compound 11 (at 0.3, 1, 3, 10 and 30 μM) for 72 h. The gray dotted line indicates 50% of cell viability. (C) The 50% inhibitory concentration (IC50) values are represented as the mean ± SD of three in dependent experiments.

    Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

    Article Title: O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia.

    doi: 10.1016/j.phymed.2022.154061

    Figure Lengend Snippet: Fig. 1. The cytotoxic effect of compound 11 against various cancer cell lines. Cell viability was measured in (A) acute leukemia cell lines: acute myeloid leukemia cells (MOLM-13 and MV4-11), acute promyelocytic leukemia cell (HL-60) and acute lymphoblastic leukemia cell (MOLT-4), and (B) solid tumor cell lines: ovarian (A2780), breast (MDA-MB-231), colorectal (HCT116) and pancreatic (AsPC-1) cancer cells. All cell lines were treated with compound 11 (at 0.3, 1, 3, 10 and 30 μM) for 72 h. The gray dotted line indicates 50% of cell viability. (C) The 50% inhibitory concentration (IC50) values are represented as the mean ± SD of three in dependent experiments.

    Article Snippet: Human AML cell lines (MOLM-13 and MV4-11), a human acute lymphoblastic leukemia cell line (MOLT-4), a human acute promyelocytic leukemia cell line (HL-60) and a human ovarian cell line (A2789) were purchased from American Type Culture Collection (ATCC, Manassas, VA, USA).

    Techniques: Concentration Assay